Cannabinol or CBN is the most prevalent cannabinoid along with CBD and THC and is created as a byproduct of THC. In fact, the oxidation of THC after being exposed to the atmosphere results in a degradation process that alters THC into CBN which can be the reason behind the sedative effect which aged cannabis possess. An excavation of a 2700 year dated grave in China disclosed preserved cannabis which had a higher concentration of CBN compared to other cannabinoids. Cannabinoids are accountable for the wide spectrum of medicinal and health reliefs through their interaction with the human physiology regulated by the ECS or endocannabinoid system, and the bunch of receptors that operates to control health and encourage homeostasis all over the body. CBN also holds an array of positive health benefits to produce optimal effects in regulating pain and neuropathy.
The Common Disorder – Neuropathy
Neuropathy generally stems from an impairment of the peripheral nerves particularly those that spread through the legs, arms, toes, and fingers. Such peripheral nerve damage causes neuropathic pain and includes nerve damage to all nerves external to the brain and also the spinal cord. Such pain is chronic as the impaired nerves transmit wrong signals towards the body regarding the existence of pain. The injury to nerve fibers generally results from a tissue impairment due to trauma, ailment or infection. Sufferers of neuropathic pain often mention it as a stinging, burning, shooting or tingling and numbing.
Causes Of Neuropathic Pain
Neuropathy can result from various causes, a familiar one being diabetes, though peripheral neuropathy can also develop from toxic trauma like chemotherapy or routine injury like carpal tunnel syndrome. Neuropathy can also originate from nerve pressure like sitting in one posture for a long duration or from conditions in which some nerves get inflamed, pinched or compressed like in sciatica. Nerve pain or neuropathic pain can even be induced by trauma such as injury of the spinal cord, where nerves receive injury, damage or detached. At times, medication also causes crippling nerve pain which can be controlled by decreasing the dosing of the disturbing drug or removing it from your medication.
Symptoms Of Neuropathy
Neuropathy shows the following symptoms as this condition affects the nerve cells which includes constant pain, dullness, a problem in maintaining body balance, tingling feeling, temperature sensitivity and experiencing pain and sensitivity from any contact with objects. Other signs of neuropathy are a problem in resting or sleep, emotional issues due to chronic pain, sleep deprivation and problem in expressing the way a person feels.
The Healing Powers Of CBN In Neuropathy
The organic plant compound CBN treats neuropathic pain effectively as it attaches to the endocannabinoid receptors extending all over the body and the brain that are accountable for regulating numerous physiological body mechanisms, such as pain, memory, appetite and mood swings to name a few. This makes this cannabinoid an effective treatment for a condition like neuropathy, which is otherwise not so simple to treat.
A Powerful Antidepressant
Antidepressant drugs have been prescribed to treat the manifestations of neuropathic pain. CBN is a potent antidepressant that targets the particular serotonin receptor and capsaicin receptors which treat effectively chronic pain. In fact, pharmaceutical antidepressants like tricyclic antidepressants work by augmenting both serotonin and norepinephrine.
Alters The Response Towards Injury
After nerve injury, the cells transmitting the nerve impulses or neurons become more responsive by a process referred to as sensitization. This procedure results in a spurt of cellular events that generates pain-sensitive nerve endings. Cannabinoids like CBN can help in reducing pain by altering such cellular events and also curb nociceptive conduction inside the spinal cord.
Works Like An Anticonvulsant And An Analgesic
CBN acts like an anticonvulsant, as anti-seizure medications are at times applied to counter neuropathic pain. Researches hold that anticonvulsants intervene with the signals of pain and halt the defective transmissions. CBN also operates upon the cannabinoid receptors CB2, which play a significant part in regulating inflammation. By elevating cannabinoids inside your body, inflammation can be curbed and spasms reduced. Our muscle movement is regulated by the motor nerves and by working as a muscle relaxant CBN helps in muscle motility and protects the injured nerve as it possesses neuroprotectant protectant. Besides, as an analgesic or pain reliever, CBN can lower both nociceptive and neuropathic pain.
Conclusion On CBN For Neuropathy
Neuropathy no doubt brings painful sensations due to the nature of damage or injury caused to the nerves. Any metabolic irregularities inside the nerve results in pro-inflammatory responses, cytokine release and relocation of macrophages that are responsible for making the immune system vigilant. Such conditions result in neuropathy and CBN has a host of anticonvulsant, analgesic, neuroprotective and antidepressant property which helps in controlling neuropathic pain without any risk of adverse effects.